P-33: Ameliorative Effects of Ethyl Pyruvate on Testis Histochemistry, Serum Superoxide Dismutase and Testosterone in Chemotherapeutic Mice

Background Infertility and fertility decline are quite a conundrum for medicine, rampant among 10-15 percent of couples. In about 40 percent of cases, men are the main culprit. Since sperm production disorders are the focal cause of man infertility, insights into these disorders and taking action to ameliorate the situation is quite vital. The current study concentrates on infertility due to sperm malformation. MaterialsAndMethods In this cross sectional-descriptive analysis, natural morphology and sperm malformation are the elements which are material to the investigation. Over a span of six months, the semen of 478 patients who referred to the center of infertility ACECR-Arak is meticulously assessed. The analyses were used applying Papanicolaou stains method and in compliance with WHO canons. Results In this study 3.83 ± 3.21 percent of sperms are morphologically natural. From among 96.17 ± 3.27 percent of malformed sperms, 5.65 ± 3.2 percent have anomaly in their heads, 4.4 ± 3.5 percent in their torso and 5.21 ± 3.7 percent have anomalies in their tails. 80.9 ± 14.5 percent of sperms are also classified as amorphous. Conclusion Current study clearly demonstrated that the higher the levels of morphological disorders, the less the chances of a fecund pregnancy. To show sound judgment, indepth analysis of all related characteristics of semen is a must. Factors like genetic background, different diseases and pollutants can devastatingly affect morphological parameters of the sperm. Stress Oxidative is just one of the mechanism leading to this anomaly.